一锅多组分合成咪唑并吡咯并[2,3-d]嘧啶酮

来源 :中国化学会第九届全国有机化学学术会议 | 被引量 : 0次 | 上传用户：chinababay

【摘要】

：

吡咯并[2,3-d]嘧啶是一类重要的含氮杂环化合物,其衍生物具有广泛的医药、生物活性,一些化合物不仅具有抗癌作用[1],还可以治疗风湿性关节炎、牛皮癣、糖尿病等疾病[2].目前,

【作者】

：

姚欢李加荣

【机构】

：

北京理工大学化工与环境学院北京100081

【出处】

：

中国化学会第九届全国有机化学学术会议

【发表日期】

：

2015年7期

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吡咯并[2,3-d]嘧啶是一类重要的含氮杂环化合物,其衍生物具有广泛的医药、生物活性,一些化合物不仅具有抗癌作用[1],还可以治疗风湿性关节炎、牛皮癣、糖尿病等疾病[2].目前,此类化合物一般以呋喃衍生物[3]、吡咯衍生物[4]等为前体物经缩合、环化多步转化而成,这些方法普遍存在条件苛刻、过程复杂、收率低等缺点.

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