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It has been reported that deep geomagnetic field (GMF) shielding, i.e.hypomag-netic field (HMF, < 2 μT), can interfere the function of central nervous system (CNS), e.g.inducing amnesia in Drosophila and chicks, disrupting circadian rhythm in bird and human, and reducing the stress induced analgesia in mice.However, the cellular and molecular mechanisms of the HMF effects on CNS remain unclear.Our lab has established a hypo-magnetic cell culture system (< 500 nT) and observed that the proliferation of human neuroblastoma cells was accelerated in the HMF.