【摘 要】
：
目的:探讨藿香正气滴丸治疗功能性消化不良(痰湿中阻证)临床疗效及调节胃排空作用.方法:功能性消化不良餐后不适综合征(FD)痰湿中阻证共218例,按分层区组随机、平行对照、双盲双模拟、多中心临床研究的方法,以1:1比例分为试验组和对照组,治疗组109例采用口服藿香正气滴丸及舒丽启能模拟剂;对照组109例采用舒丽启能片剂口服及藿香正气滴丸模拟剂,疗程为4周.疗后观察两组的临床疗效.用药前日行胃排空检查
【出 处】
：
世界中医药学会联合会消化病专业委员会第四届消化病国际学术大会
论文部分内容阅读
目的:探讨藿香正气滴丸治疗功能性消化不良(痰湿中阻证)临床疗效及调节胃排空作用.
方法:功能性消化不良餐后不适综合征(FD)痰湿中阻证共218例,按分层区组随机、平行对照、双盲双模拟、多中心临床研究的方法,以1:1比例分为试验组和对照组,治疗组109例采用口服藿香正气滴丸及舒丽启能模拟剂;对照组109例采用舒丽启能片剂口服及藿香正气滴丸模拟剂,疗程为4周.疗后观察两组的临床疗效.用药前日行胃排空检查并对其中74例胃排空障碍的病例于第28日行胃排空复查.
结果:1.证候疗效的总有效率两组相当,2周访视点,治疗组为78.9％、对照组为72.48％.4周访视点,治疗组为93.58％、对照组为93.58％.2周、4周访视点证候积分和情况比较,组间差异均无显著性统计学意义;组内提示4周疗效优于2周疗效.2.两组均能改善功能性消化不良的临床症状,单项证候的整体疗效分析显示腹胀、口淡不渴等证候改善程度治疗组优于对照组.3.两组治疗后胃排空均有改善,组间比较差异无显著性统计学意义.
结论:藿香正气滴丸能改善痰湿中阻型功能性消化不良患者的临床症状,部分单项症状疗效优于舒丽启能.藿香正气滴丸、舒丽启能均能有效改善胃排空减缓的状态,提示藿香正气滴丸有调节胃肠运动的作用.
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