Delivery of AAV9 cyclin-A2 via hyaluronic acid hydrogel induces cardiac regeneration as well as impr

来源 :2013中国心脏大会(CHC) | 被引量 : 0次 | 上传用户：lavina0526

【摘要】

：

【作者】

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Xiang Ma

【机构】

：

First Affiliated Hospital of Xinjiang Medical University Department of Coronary Heart Disease

【出处】

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2013中国心脏大会(CHC)

【发表日期】

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2013年2期

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Objective To assess the effects of exogenous AAV9 Cyclin-A2 in vivo post MI.Methods Forty-eight male Sprague Dawley rat were randomly divided into four groups: MI+PBS (n =12); MI+AAV9 Cyclin-A2 (n =12); MI+HA (n =12); MI+HA+AAV-9 Cyclin-A2 (n =12).The recombinant was constructed, and 2 x 1011 genome copies constructs were injected into the infarcted myocardium at three different points.

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Delivery of AAV9 cyclin-A2 via hyaluronic acid hydrogel induces cardiac regeneration as well as impr

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