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The mechanical behavior of freestanding(FS)two-dimensional(2D)materials is typically investigated using the indentation test performed by atomic force microscopy(AFM).It is shown that the boundary condition has dramatic effect on the indentation response of FS 2D-materials; in particular,the usual assumption of a clamped boundary condition should be replaced by an adhesive boundary condition due to the van der Waals(vdW)interactions between 2D-materials and their substrates.