Muscularization of Pulmonary Artery and RhoA/ROCK levels in Rats Exposed to Intermittent Hypoxia

来源 :中国睡眠研究会第九届学术年会 | 被引量 : 0次 | 上传用户:sscy2002
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  Objective: Intermittent hypoxia (IH), as the most important pathophysiologic characteristic of obstructive sleep apnea (OSA) and a recognized risk factor for cardiovascular disorders, may lead to proliferation of smooth muscle cells (SMCs) and then pulmonary arterial remodeling through the RhoA/ROCK signaling pathway.
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