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Objective: To establish a high effect database of epilepsy that can storage patients' information permanently and service for clinical therapy and scientific research.Methods :UsingMySQL to establish the relational database.Results :The system records the patients' information fully, displays the dynamic medical operation; and it is easy to query and communication between doctors and patients.Corclusion : The system significantly improves the efficiency of clinical and research work, enhances the utilization of epilepsy data, and achieves digital management as well as sharing of the epilepsy data, and it provides a guide to the medical therapy and scientific research, and makes the knowledge regarding epilepsy familiar to the patients.