【摘 要】
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Clinical studies have demonstrated that conditionally replicating adenovirus is safe.We constructed an oncolytic adenovirus, Ad-hTERT-E1 a-Apoptin, using a cancer-specific promoter (human telomerase r
【机 构】
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Institute of Military Veterinary, Academy of Military Medical Sciences of PLA
【出 处】
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中国免疫学会第九届全国免疫学学术大会
论文部分内容阅读
Clinical studies have demonstrated that conditionally replicating adenovirus is safe.We constructed an oncolytic adenovirus, Ad-hTERT-E1 a-Apoptin, using a cancer-specific promoter (human telomerase reverse transcriptase promoter,hTERTp) and a cancer cell-selective apoptosis-inducing gene (Apoptin).Ad-hTERT-E1a-Apoptin was proven effective both in vitro and in vivoin our previous study.
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