Biodistribution of Doxorubicin-Loaded Cell Penetrating Peptide Modified Ph-sensitive Liposomes and I

来源 :纳米药物及纳米生物技术国际学术大会暨中国药学会纳米药物专业委员会成立大会 | 被引量 : 0次 | 上传用户：ieven1989

【摘要】

：

【作者】

：

Dan Sun Yuang Ding Guiling Wang Ying Xie

【机构】

：

Department of Pharmaceutics, School of Pharmaceutical Science, Peking University, Beijing,China, 100

【出处】

：

纳米药物及纳米生物技术国际学术大会暨中国药学会纳米药物专业委员会成立大会

【发表日期】

：

2015年11期

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It is a potential strategy to increase the selectivity of cell penetrating peptide (CPP) to tumor by the regulation of PEG-Hz-DSPE on the surface of liposomes.In this work, we developed an efficient PEGylated liposomal nanocarrier (CPPL) containing CPP and pH-sensitive hydrazone bond to enhance doxorubicin (DOX) tumor-targeted delivery in vivo.

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Biodistribution of Doxorubicin-Loaded Cell Penetrating Peptide Modified Ph-sensitive Liposomes and I

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