Smooth-muscle BMAL1 participates in blood pressure circadian rhythm regulation

• 作 者: Zhongwen Xie Wen Su Shu Liu Guogang Zhao Karyn Esser Elizabeth A.Schroder Mellani Lefta Harald M.Stauss Zhenheng Guo Ming Cui Gong
• 机 构: Department of Physiology, College of Medicine, University of Kentucky, Lexington, Kentucky, USA;Key
• 出 处: 华东地区第十四届实验动物科学学术交流会
• 发表日期: 2016年11期

　　As the central pacemaker,the suprachiasmatic nucleus (SCN) has long been considered the primary regulator of blood pressure circadian rhythm;however,this dogma has been challenged by the discovery that each of the clock genes present in the SCN is also expressed and functions in peripheral tissues.The involvement and contribution of these peripheral clock genes in the circadian rhythm of blood pressure remains uncertain.