Efficacy of extracorporeal shock wave therapy for the treatment of Peyronie's disease: a meta a

• 作 者: Hesong Dai Yutian Dai
• 机 构: Nanjing Drum Tower Hospital,Nanjing 210008,China
• 出 处: 华夏医学论坛·泌尿生殖2015暨亚太性医学年会2015
• 发表日期: 2015年6期
• 关键词: Meta-analysis extracorporeal shock wave therapy (ESWT) Peyronie's disease (

　　Objective: Extracorporeal shock wave therapy(ESWT)is an attractive treatment for Peyronies disease(PD),while its effectivity for PD still remains controversial.Methods: We conducted a search of PubMed,MEDLINE,EMBASE for available literatures published before June 2014.To access the treatment of ESWT for PD in penile pain,plaque size,deviation angle,intercourse function.Results: Seven studies were finally assessed in our metaanalysis.When Compared ESWT with control for penile pain,the remission rate was significantly higher(OR =1.78,95%CI,1.34-2.35),unchanged pain rate were significantly less(OR =0.51,959%CI,0.30-0.89)and aggravation pain rate was less(OR =0.38,95%CI,0.12-1.17).The pooled odds risk for reduced deviation angle rate was(OR =1.36,95%CI,0.80-2.31)in the ESWT group vs control,which indicates no statistical significance.Contractible or disappeared plaque rate after ESWT were significantly higher than in control group(OR =2.42,95%CI,1.74-3.37).There was no significant difference for the rate of possible intercourse patients between ESWT and control group(OR =1.32,95%CI,0.42-4.17).Moderate intercourse rate were significantly lower after ESWT vs.control group(OR =0.65,95%CI,0.42-0.99).Impossible intercourse rate were no statistical significant difference(OR =0.811,95%CI,0.42-1.58).Conclusions: ESWT could alleviate penile pain and reduce or soften PD plaque.The intercourse or erectile function may subjectively improve after ESWT.However,there is no significant influence for penile deviation.More high-quality RCTs are required to verify the findings.