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Background The study sought to assess the five-year clinical impact of complete (CR),incomplete (ICR) revascularization,and reasonable ICR (R-ICR) in patients with unprotected left main coronary artery (ULMCA) disease treated with drug-eluting stents (DES).Methods A total of 910 consecutive patients with ULMCA disease undergoing DES implantation were prospectively enrolled in this study.Angiographic CR was defined as revascularization in all diseased segments with diameter ≥1.5 mm (CR-1,according to the Synergy between PCI with Taxus and cardiac surgery (SYNTAX) classification) or ≥2.5 mm (CR-2).R-ICR was defined as patients having a diameter stenosis ≥50％ post treatment in diseased segments with diameter between 1.5 mm and 2.5 nun.The primary endpoint was the incidence of major cardiac adverse event (MACE: a composite of cardiac death,myocardial infarction (MI) and target vessel revascularization) at 5-year follow-up.