In silico analysis of the inhibition of KRAS-PDEδ interactions

来源 :The 15th ICQC International Congress of Quantum Chemistry(第1 | 被引量 : 0次 | 上传用户：lhdbbc

【摘要】

：

【作者】

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E.Boz N.(S).Tüzün S.Durdagi

【机构】

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Department of Chemistry,Faculty of Science and Letters,Istanbul Technical University,Maslak,Istanbul

【出处】

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The 15th ICQC International Congress of Quantum Chemistry(第1

【发表日期】

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2015年5期

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About 30％ of all human cancers are directly related to several RAS mutations and abnormal cell signalling.RAS is one of the proto-oncogenes of GTPase family which regulates signalling network and cell proliferation.Signalling activity of KRAS is dependent on its enrichment level on the plasma membrane(PM).

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In silico analysis of the inhibition of KRAS-PDEδ interactions

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