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The incidence of overweight conditions among children and adolescents is a growing concern worldwide.This study included a systematic literature review and meta-analysis of experimental randomized controlled studies of child and adolescent weight-related health interventions.The characteristics of interventions were considered, and the measurement data were extracted for collective analyses.The effectiveness of interventions at reducing participant body mass indexes was evaluated, and the roles of parents levels of participation in the interventions were examined.A wide array of activities was included among the interventions, and significant differences in effectiveness existed among levels of parental participation.Intervention duration also positively predicted effectiveness and further strengthened the model.The empirical evidence in this study indicates that weight-related health interventions for children and adolescents are more successful at reducing participants body mass indexes when parent participation is required, even when controlling for the duration of interventions.This study offers implications for professional practice, community health programming, and parenting education.Also, the need for exploration into novel areas of study is established.