GADD45G负调控JAKSTAT3通路及诱导肝癌细胞衰老的研究

来源 :第一届国际实验生物学和医学论坛 | 被引量 : 0次 | 上传用户：madeshabi

【摘要】

：

GADD45g: Growth Arrest and DNA Damage-inducible 45-γ 生长阻滞和DNA损伤诱导基因GGADD45 家族:·GADD45a,GADD45b和GADD45g;·高度同源性(55％-57％同源性),但是位于不同染

【作者】

：

刘永忠

【机构】

：

上海交通大学医学院,仁济医院上海市肿瘤研究所

【出处】

：

第一届国际实验生物学和医学论坛

【发表日期】

：

2013年10期

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GADD45g: Growth Arrest and DNA Damage-inducible 45-γ 生长阻滞和DNA损伤诱导基因GGADD45 家族:·GADD45a,GADD45b和GADD45g;·高度同源性(55％-57％同源性),但是位于不同染色体上;·对环境或生理刺激有不同的反应;·在多数的实体肿瘤和造血系统恶性肿瘤中,GADD45家族的表达量不降.GADD45调控的应激反应.

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GADD45G负调控JAKSTAT3通路及诱导肝癌细胞衰老的研究

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