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  5. Inducing antivascular effects in tumors with ultrasound stimulated micron sized bubbles

Inducing antivascular effects in tumors with ultrasound stimulated micron sized bubbles

来源 :2015两岸超声技术与医学研讨会 | 被引量 : 0次 | 上传用户：areyoureadygolaopo
【摘 要】
：
Background, Motivation and Objective It has been demonstrated that relatively low intensity ultrasound in combination with microbubbles is capable of inducing a vascular shutdown in preclinical tumors
【作 者】
：
Naomi Matsuura Minseok Seo Niroo Sivapalan Siqi Zhu Ben Leung David Goertz 
【机 构】
：
Medical Imaging, University of Toronto, Canada Su
【出 处】
：
2015两岸超声技术与医学研讨会
【发表日期】
：
2015年5期
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Background, Motivation and Objective It has been demonstrated that relatively low intensity ultrasound in combination with microbubbles is capable of inducing a vascular shutdown in preclinical tumors, and that this can lead to growth inhibition. In previous reports we have shown that this effect can be coupled with anticancer agents to achieve potent antitumor effects, by a means that is not linked to increases in drug uptake (Todorova et al Int J Cancer 2013; Goertz et al Plos One 2012).
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