【摘 要】
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Objective: The new oral multi-kinase inhibitor REG improves overall survival (OS) in mCRC patients who progress after standard therapies.CONCUR (NCT01584830) evaluated the efficacy and safety of REG i
【机 构】
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Sun Yat-Sen University Cancer Center, Guangzhou, China
【出 处】
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第十七届全国临床肿瘤学大会暨2014年CSCO学术年会
论文部分内容阅读
Objective: The new oral multi-kinase inhibitor REG improves overall survival (OS) in mCRC patients who progress after standard therapies.CONCUR (NCT01584830) evaluated the efficacy and safety of REG in Asian patients with mCRC.Here we report outcomes in Chinese patients.Methods:Patients with mCRC who progressed after completing standard therapy were randomized (2∶1) to REG 160 mg daily or placebo during the first 3 wks of each 4-wk cycle.Patients must have had ≥2 prior standard treatments including a fluoropyrimidine, oxaliplatin and irinotecan.
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