论文部分内容阅读
The lipoxin receptor agonist BML-111 protects against LPS/D-GaIN-induced acute liver injury in rats
【机 构】
：
Medical College of Nanchang University Department of Pharmacology,Nanchang 330006,China
【出 处】
：
中国病理生理学会第十四届肿瘤专业委员会、第十五届免疫专业委员会联合学术会议
【发表日期】
：
2014年4期
其他文献
The role of Mitogen-and Stress-Activated Kinase 1 in Epstein-Barr virus latent membrane protein-1-pr
Objective: The Mitogen-and Stress-Activated Kinase 1(MSK1)-mediated nucleosomal response plays a critical role in connecting extracellular signals with gene expression.However,the role of MSK1 in mali
细胞癌变与核外的遗传物质即线粒体DNA(mitochondrial DNA,mtDNA)的突变和功能紊乱可能也有关系.细胞色素C氧化酶(cytochrome c oxidase,COX)是控制线粒体呼吸和能量代谢的关键酶.前期通过cDNA微阵列检测,发现胃癌中存在一个EST片段表达缺失或减弱,然后对这一胃癌相关的EST片段(MDSCBC11)所代表的基因进行克隆和表达分析.利用多组织Norther
Up-regulation of Glioma-associated oncogene homolog 1 expression by serum starvation promotes cell s
Tumor microenvironment is characteristic of ischemia and starvation of nutrient.Glil is a strong positive transcriptional activator of the downstream of Hedgehog (Hh) signaling pathway and plays an es
会议
目的:EB病毒是一种人类疱疹病毒,与多种淋巴增生性疾病如传染性单核细胞增多症和淋巴瘤以及鼻咽癌等恶性肿瘤密切相关.EB病毒对于上皮细胞和淋巴细胞的恶性转化作用与其潜伏状态密切相关.本研究旨在探讨在缺氧和紫外照射的条件下，miR-18a在EBV潜伏中的作用以及这种作用是否通过p53促进EBV的潜伏作用。方法:体外培养BJAB,P3HR1,RAJI三株淋巴瘤细胞系，分别过表达或封闭miR-18a的表达
本实验室前期以太空诱变后生物学性状发生了改变的宫颈癌Caski细胞株48A9作为Tester,地面常规对照组宫颈癌Caski细胞株作为Driver构建消减杂交文库,通过反向Northern杂交成功筛选得到多个差异表达基因.经后期分析发现一条长为754bp的片段,存在于2号染色体2q37.1位置,无已知基因与其同源,3端存在加尾信号AATAA及polyA尾,暂时命名为C4,值得进一步研究。目的:通过
肿瘤微环境中普遍存在着缺血缺氧和营养缺乏.Gli1是Hedgehog信号通路下游比较强的起正性调控作用的转录因子,在包括乳腺癌在内的多种肿瘤的发生发展中起到重要作用.本文利用两株ER阳性的乳腺癌细胞MCF-7和T47D研究了Gli1在血清饥饿条件下的促存活效应及其分子机制.结果显示,血清饥饿能够通过活化的PI3K/AKT通路显著上调MCF-7和T47D细胞中Gli1的表达.过表达Gli1可以促进G
Immunotherapy is one of the most promising new therapies for hepatocellular carcinoma (HCC) in recent years.In this study,folate-conjugated chitosan nanoparticles (FA-CS-NPs) were loaded with mouse in
Aquaporin 5 (AQP5) promotes the progression and invasion of several cancers,but its role in the tumorigenesis of human gastric carcinoma (GC) has not been clearly defined.Here,we investigated the pote
Fibroblast-like synoviocytes from adjuvant arthritis rat were transfected with plasmid over-expresse
Objective Fibroblast-like synoviocytes from adjuvant arthritis (AA) rat were transfected with plasmid over-expressed TIPE2+/+,then apoptosis mediated by TIPE2 on DR5 and its pathological role in Adjuv