声脉冲辐射力成像评价肝纤维化和肝硬化的临床价值

来源 :中华医学会第十五次全国超声医学学术会议 | 被引量 : 0次 | 上传用户:sw
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目的:探讨声脉冲辐射力成像(acoustic radiation force impulse,ARFI)技术在无创评估慢性肝病患者肝纤维化及肝硬化严重程度的临床应用价值.方法:采用ARFI技术检测186例患者的肝脏弹性参数(Vs),以肝纤维化病理分期为金标准进行分组,其中90例肝硬化患者根据Child-Pugh评分进一步分为代偿期及失代偿期肝硬化组.比较肝弹性参数与肝纤维化程度和肝静脉压力梯度(hepatic vein pressure gradient,HVPG)的相关性.结果:ARFI所测各组肝Vs分别为:S0期1.06±0.17m/s、S1期1.18±0.14m/s、S2期1.24±0.16m/s、S3期1.44±0.25m/s、S4期1.94±0.42m/s(代偿组1.77m/s±0.38、失代偿组2.11±0.50m/s).除S0与S1期外,其余各组间弹性参数差异均有统计学意义(P<0.01).
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