【摘 要】
:
Triple-negative (TN) breast carcinoma, characterized by estrogen receptor, progesterone receptor, and HER2 negativity, is a group of aggressive tumors.TN br
【机 构】
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Diagnostic Immunohistochemistry Laboratory Image and In Situ Hybridization Analysis Laboratory The U
【出 处】
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2011第四届世界癌症大会暨乳腺癌峰会
论文部分内容阅读
Triple-negative (TN) breast carcinoma, characterized by estrogen receptor, progesterone receptor, and HER2 negativity, is a group of aggressive tumors.TN breast cancer is associated with a higher recurrencerate and shorter survival and lacks the benefit of specific therapy.TN tumors usually express high levels of Ki-67 and p53 that are considered prognostic markers for breast cancer.We compared Ki-67 and p53 expression between TN and high-grade non-TN invasive carcinomas in a total of 214 cases and investigated an association between their expression and axillary nodal metastasis in these tumors.
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