【摘 要】
：
人们越来越重视由于放化疗对于卵巢功能的损伤、卵巢早衰、卵巢先天发育不良或缺如、病理性卵巢切除及更年期综合征及其带来的后果.当前主要研究卵巢功能保护和保存的两个方面.卵巢功能保护主要有药物干预治疗和卵巢组织异位移殖.保存方法主要有:胚胎冷冻、卵子冷冻、卵巢组织冷冻.相比之下,冷冻卵巢组织在保存生育力及恢复内分泌方面较其他技术具有更大的潜力.目前,卵巢组织冷冻方法包括慢速程序化冷冻和快速玻璃化冷冻,这
【机 构】
：
大连市妇产医院生殖中心 116000
【出 处】
：
中华医学会第七次全国生殖医学学术会议
论文部分内容阅读
人们越来越重视由于放化疗对于卵巢功能的损伤、卵巢早衰、卵巢先天发育不良或缺如、病理性卵巢切除及更年期综合征及其带来的后果.当前主要研究卵巢功能保护和保存的两个方面.卵巢功能保护主要有药物干预治疗和卵巢组织异位移殖.保存方法主要有:胚胎冷冻、卵子冷冻、卵巢组织冷冻.相比之下,冷冻卵巢组织在保存生育力及恢复内分泌方面较其他技术具有更大的潜力.目前,卵巢组织冷冻方法包括慢速程序化冷冻和快速玻璃化冷冻,这两种冷冻方法相对成熟,但这两种方法哪个效果更好,国内外还没有统一通用的冷冻方案,存在颇多不同意见.且移植技术及其移植后生殖和内分泌功能的恢复效果也有待提高.综合近年来卵巢组织冷冻保存研究的进展现状,探讨目前存在的问题及应用前景,探讨如何为临床应用提供最佳的冷冻方案.
其他文献
糖尿病是当前威胁全球人类健康的最重要的慢性非传染性疾病之一.据国际糖尿病联盟(IDF)的统计表明,目前全球约3.82亿人患糖尿病,仅2013年,全球有510万人死于与糖尿病相关的疾病,占所有死亡人数的8.39％.而中国2013年糖尿病的患病人数为9840万,居全球首位;IDF估计,到2035年中国的糖尿病患病人数将达到1.43亿.DPP4抑制剂是治疗Ⅱ型糖尿病的新药,因其无低血糖、体重增加、水肿以
The cytochrome P450 enzyme CYP3A4 is highly expressed in the intestinal mucosa, where it plays a critical role in the firstpass metabolism of orally administered drugs and thereby influences systemic
Ain The present study developed a CYP3A4expressed Caco2 monolayer model at which effects of the effluxmetabolism alliance on the transport and uptake of clausenamide(CLA) enantiomers as CYP3A4 substra
Aim To investigate the intraindividual variation in activities of cytochrome P450 enzymes (CYP) in human liver microsomes (HLM).Methods GYP s relative Km, Vmax and GLint (n =105) expressing as relativ
Aim Paeoniflorin6′ Obenzene sulfonate (CP25) was synthesized to improve oral absorption.This study was performed to investigate absorptive behavior and mechanism of CP25 in intestine.Methods The effec
Aim The aim of this study was to evaluate the pharmacogenetic variability in the disposition of felodipine in healthy Chinese subjects.Methods A single oral dose of 5 mg felodipine was orally administ
Aim Paeoniflorin (PF) and albiflorin (AF) are the main components of total peony glucosides(TPG), which has been widely used as the valuable monoterpene glycosides in Paeonia lactiflora Pall and have
Aim Clopidogrel therapy is associated with a substantial variability in pharmacokinetics (PK) and pharmacodynamics (PD) responses.To date, known gene variants explain only a small proportion of the va
Objective To evaluate whether delayed initiation of gonadotropin in luteal long protocol affected the outcome of in vitro fertilization (IVF).Study design Prospective randomized study at the reproduct
Background To evaluate basal testosterone (T) levels in women undergoing in vitro fertilization (IVF)cycles and examine the association between basal T levels and ovarian response or IVF pregnancy out