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Background:Pretreatment serum LDH was predictive of survival or distant metastasis among patients with non-metastatic NPC.But the predictive value of serum LDH after treatment was unknown.Hence, the purpose of this study was to examine the relationships between follow-up serum LDH and loco-regional control, distant metastasis-free survival (DMFS), and overall survival among patients with non-metastatic NPC after IMRT.