Ti-Cu-O薄膜的制备和结构及血液相容性的研究

来源 :第十一届全国表面工程大会暨第八届全国青年表面工程学术会议 | 被引量 : 0次 | 上传用户:tysystem
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  与血液直接接触的介入材料存在血液相容性不足等问题,研究发现通过材料表面改性方法,可以有效提高传统材料的抗凝血性能。研究发现,Ti-O系薄膜是一种具有良好的生物相容性的新型材料,将其沉积在血管支架等心血管材料的表面,可以有效提高其血液相容性。铜离子可有效催化血管内皮细胞释放NO,进而抑制血小板的激活与聚集,改善抗凝血性能。在氧化钛薄膜具有较好的抑制血小板粘附的基础上,在不锈钢和硅片基体上沉积Ti-(Cu)-O薄膜。以氧化钛薄膜作为对照样,讨论含铜量改变对Ti-(Cu)-O薄膜显微结构、膜基结合力、耐腐蚀性、铜离子释放、催化释放NO以及血液相容性等影响。
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