【摘 要】
：
The aim of this study was to perform a head-to-head comparison of efficacy and safety profile between 60 mg denosumab (Den) subcutaneously (SC) per 6 months (Q6M) and 70 mg alendronate (Aln) orally pe
【出 处】
：
中华医学会第五次中青年骨质疏松和骨矿盐疾病学术会议
论文部分内容阅读
The aim of this study was to perform a head-to-head comparison of efficacy and safety profile between 60 mg denosumab (Den) subcutaneously (SC) per 6 months (Q6M) and 70 mg alendronate (Aln) orally per week (QW) for postmenopausal women with low bone mineral density.We searched electronic databases comparing efficacy and safety of Den SC Q6M and Aln QW in postmenopausal women.
其他文献
目的 骨转换生化指标(Bone turnover biochemical markers,BTMs)是骨质疏松症鉴别诊断与治疗中的重要评价参数.本研究旨在中国健康人群中建立不同性别、不同年龄段血清Ⅰ型原胶原氨基端肽(PINP)和Ⅰ型胶原C末端肽交联(β-CTX)正常参考值,并探讨其影响因素.
Aseptic loosening (AL) is the single most common complication of total joint arthroplasty.The critical factor may contribute to loosening is the adverse tissue response to wear debris.A growing body o
目的 探讨骨质疏松性椎体压缩性骨折患者单侧与双侧椎弓根入路经皮穿刺椎体成形术两种穿刺方法的特点、临床疗效及应用价值.方法 回顾分析2007年12月-2011年2月我院收治并获得6个月以上随访的56例骨质疏松性单个椎体压缩性骨折女性患者的临床资料,其中A组30例,采用单侧椎弓根入路经皮穿刺椎体成形术治疗;B组26例,采用双侧椎弓根入路经皮穿刺椎体成形术治疗,所有患者术前视觉模拟疼痛评分(VAS),对
Objective We probed the relation between age and 1,25-dihydroxyvitamin D receptor (VDR) expression in freshly removed human bone.Methods We collected biopsy specimens of the femur neck taken at surger
目的 观察高铁环境(枸橼酸铁铵)对人成骨细胞铁稳态、氧化应激的影响,探讨两者之间的相互关系.方法 人成骨细胞(hFOB 1.19)培养后,用不同浓度枸橼酸铁铵(0umol、/L、50umol/L、100umol/L、200umol/L)加入细胞培养基中,用RT-PCR检测成骨细胞铁调节基因膜转铁蛋白(FPN1)、转铁蛋白受体(TfR)和二价金属转运蛋白1(DMT1)的表达变化;激光共聚焦扫描显微镜
目的 评估以OSTA指数确定的不同骨松风险男性患者骨定量超声相关指标及骨密度(BMD)的特点.方法 50岁以上男性合格研究对象724例,完成身高、体重、足跟骨定量超声(QUS)测定.120例行DXA法BMD测定.以OSTA指数划分低危组、中危组和高危组,以WHO骨质疏松诊断标准,分为骨量正常组,低骨量组和骨质疏松组,比较组间BMD、QUS-T score及QUI的差异;OSTA与QUS-T sco
Objective To study the inconsistency of tested parts being chosen in clinic diagnosis,and the changes or regulations in T-scores of hip and lumbar by DXA in different aged people by retrospective anal
目的 探讨北京某社区汉族男性钙调激素及骨转换指标的变化特征.方法 回顾性分析2012年北京某社区2792例汉族男性查体人群的一般资料、钙调激素(25羟维生素D[25OHD]、甲状旁腺素[PTH])及骨转换指标(Ⅰ型原胶原氨基末端肽[PINP]、骨钙素[OC]、胶原C端交联物[CTX])的测定结果,根据年龄分组,比较各年龄组间上述指标的差别,分析随增龄钙调激素及骨转换指标的变化趋势,以及维生素D营养
Objective To analyse the difference and change rule in T-scores of hip s and lumbar s bone mineral density with ageing in 1150perimenopausal period and senile women in south of Jiangsu Province, and p
目的 探讨绝经后妇女甲状旁腺素基因(PTH)BstB Ⅰ多态性与骨密度的关系.方法 用双能X线骨密度仪检测141例绝经后妇女的腰椎,股骨颈,大转子和Wards三角骨密度,应用PCR-RFLP技术检测PTH基因BstBⅠ多态性.结果 ①PTH基因型分布频率为BB型68.8％、Bb型24.1％、bb型7.1％.