Polymer-grafted mesoporous silica hybrid nanoparticles as hypoxia-responsive drug carriers

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户：pianolaz

【摘要】

：

【作者】

：

Feng Yu Huijing Wu Yufang Xu Xuhong Qian Weiping Zhu

【机构】

：

State Key Laboratory of Bioreactor Engineering,Shanghai Key Lab of Chemical Biology,School of Pharma

【出处】

：

Fourth Symposium on Innovative Polymers for Controlled Deliv

【发表日期】

：

2016年11期

【关键词】

：

mesoporous silica nanoparticles hypoxia-responsive controlled release thermo-res

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　In the recent years,the development of novel nanocarriers for biomedical applications,especially for cancer therapy,has strongly attracted the attention of the scientific community.Among them,mesoporous silica nanoparticles (MSNs) (pore size of 2-50 nm) have been widely used to construct controlled drug delivery systems[1,2].

其他文献

Thermo-sensitive hydrogel of pectin/chitosan containing gold nanoparticles for biological applicatio

Polysaccharides have been used in many biological applications due to their biocompatibility,biodegradability and non-toxicity.Considerable attention have been paid in polysaccharides including edge r

会议

hydrogelchitosanpectinscaffoldsdrug delivery

Dexibuprofen loaded PEGylated nanospheres for Alzheimer's disease treatment

Alzheimers disease (AD) is a multifactorial neurodegenerative condition which undergoes with neuroinflammatory responses[l].It has also been demonstrated that Ibuprofen prevents AD.However,Ibuprofen h

会议

nanoparticlesmdexibuprofennanospheresbraincells

Simultaneous delivery system of antigenic protein and cytokine gene using hybrid complexes of pH-sen

The induction of cancer-specific cellular immunity is crucial to achieve cancer immunotherapy.For the induction of cellular immunity,efficient antigen delivery systems to cytosol of antigen presenting

会议

pH-sensitive polymerliposomechemokinedendritic cellcancer immunotherapy

Electrospinning fabrication of bioactive scaffolds for tendon-bone healing

Anterior cruciate ligament (ACL) rupture is one of the most serious sport injuries.From a clinical point of view,autologous hamstring tendon is often applied to be fixed in the bone tunnel through the

会议

polycaprolactoneanterior cruciate ligamentnano-hydroxyapatitestem cells

Coaxial double-walled microspheres for combined release of cytochrome c and doxorubicin

Co-axial electrohydrodynamic atomization (CEHDA) can be adapted to fabricate core/shell microspheres with narrow size distribution in a single step for controlled and sustained release of therapeutic

会议

core-shell microparticlesanticancer drug deliveryprotein stability

In situ self-assembled chitosan microspheres for controlled anti-cancer drug release

5-Fluroruracil (5FU) is used as a chemotherapeutic agent in modem medicine.However,due to its low solubility at physiological pH,inclusion complexes of chitosan (CS) with 5FU was used to improve the e

会议

5-Fluorouracilchitosandrug deliveryself-assemblypharmacokinetics

Nerve-repair conduit formed of polymeric tissue-engineering fibers sustained-releasing nerve growth

For repairing severely damaged peripheral nerves (above 5 mm),surgical suture (anastomosis) is no longer feasible.And nerve transplantation (auto-graft or ectogenous graft) becomes the choice in curre

会议

nerve conduitbeaded fibersnerve growth factornative conformationsustained re

A dual inhibition of tumor growth and metastasis by CXCR-4 targeting based on redox sensitive dextri

The metastasis of breast cancer is mainly regulated by chemokine receptors such as CXCR4.As reported,neutralizing the interactions ofCXCL12/CXCR4 could significantly inhibit the metastasis of breast c

会议

dextrin nanogelCXCR4antagonistredox sensitivemetastatic breast cancer

Self-assembly of inorganic nanoparticle vesicles driven by tethered protein-polymer

Nowadays,because gold nanoparticles (AuNPs) with various functions and chemical stability could easily be synthesized,they play important roles in biomedical fields such as biocatalysis,biosensors and

会议

gold nanoparticalsprotein-polymerdrug delivery

Antifouling improvement of graphene/TiO2 modified polyurethane coatings

Polyurethane has been used as biomaterials for excellent properties and wide application potential compared to other polymers.At present,polyurethane has attracted much attention in the preparation of

会议

grapheneTiO2antifoulingpolyurethane

Polymer-grafted mesoporous silica hybrid nanoparticles as hypoxia-responsive drug carriers

其他学术论文