Proton production and transfer mechanism in [NiFe] hydrogenase

来源 :第十一届全国化学生物学学术会议 | 被引量 : 0次 | 上传用户：llz364088963

【摘要】

：

Owing to its reversible H2 oxidation reaction,hydrogenase(H2ase)is one of the most highly studied enzymes,with promising applications in future energy technologies.

【作者】

：

Hulin Tai Shun Hirota

【机构】

：

MOE Key Laboratory of Natural Resources of the Changbai Mountain and Functional Molecules,Department

【出处】

：

第十一届全国化学生物学学术会议

【发表日期】

：

2019年3期

【关键词】

：

Biocatalysis hydrogen hydrogenase IR spectroscopy proton transfer

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Owing to its reversible H2 oxidation reaction,hydrogenase(H2ase)is one of the most highly studied enzymes,with promising applications in future energy technologies.

其他文献

Improving the Spreading of Quintrione Droplets through Host-guest Interaction

Spreading of agricultural sprays on plant surfaces is a significant task,since it decreases pesticide/herbicide usage and thereby reduce the risk of environmental pollution.

会议

Dynamic Self-assemblyHost-guestQuintrioneAmino Pillar [5] Arene1-1 Spreading

Application of non-canonical crosslinking amino acids to study pyroptosis related protein-protein in

Pyroptosis is a form of regulated cell death in mammalian cells that is triggered by activation of various inflammasome complexes,leading to the activation of the proteolytic enzymes caspase-1 or casp

会议

Non-canonical crosslinking amino acidspyroptosisGSDMDcaspase-4

线粒体呼吸链超复合体的研究进展

作为呼吸链的核心，线粒体复合物Ⅰ-Ⅳ依次催化一系列氧化还原反应，保证了电子和质子的有序传递，从而为能量的高效合成提供了基础。整个过程中，复合物之间是否存在协同作用，是否发生直接接触，是线粒体研究的一个焦点和难点。

会议

呼吸链超复合体冷冻电镜

Ru(Ⅲ)complexes bearing acetylacetone and amidine ligands:A New class of anticancer agents

The use of transition-metal complexes in medicine has enjoyed extensive attention given the tremendous success of cisplatin as a chemotherapeutic agent.

会议

ruthenium complexamidineapoptosis

Multiple Site-specifically One-Pot Synthesis of Two Proteins by Bio-orthogonal Flexizyme System

Acetylation of lysine is a reversible post-translational modifications(PTMs),which plays a key role in regulating gene expression and dynamic transitions in chromatin remodeling[1].

会议

Platinum complexNMRG-quardruplexdynamic binding

new rhodium(Ⅰ)NHC complex inhibits TrxR:in vitro cytotoxicity and in vivo hepatocellular carcinoma s

Thioredoxin reductase(TrxR)is always overexpressed in different types of cancer cells including hepatocellular carcinoma(HCC)cells and regarded as a target with great promise for anticancer drug resea

会议

Rhodium(Ⅰ)-NHC complexThioredoxin reductaseReactive oxygen species

基于EDTA结构的小分子化合物选择性识别Cu2+及其在解聚Cu2+/Zn2+诱导的Aβ聚集中的应用

目前有观点认为,由Cu2+/Zn2+诱导的β-淀粉样蛋白(Aβ)聚集体的累积及其毒性,与阿尔茨海默症(AD)的发生密切相关.[1,2]基于此观点,我们以传统螯合剂乙二胺四乙酸(EDTA)为骨架,将其与荧光基团4-氧基水杨酸(4-ASA)结合,得到一个对铜离字有特异性荧光响应的化合物EDTA-ASA.

会议

铜离子识别荧光探针Aβ聚集阿尔兹海默症

The least stable pathological collagen targeted antibody-mimetic-peptide monitors collagen lesions i

Collagen is the most important structural protein in the human body.It has shown that collagen lesion is a critical step in tumor invasion and metastasis.

会议

pathological collagentumor tissuelike-antibody peptide

Switch off “Parallel Circuit”:Insight of New Strategy of Simultaneously Suppressing Canonical and No

Sepsis is a life-threatening inflammatory disease with a high mortality rate and huge implicative cost.Lipopolysaccharide(LPS)from Gram-negative bacteria activates toll-like receptor 4(TLR4)and may tr

会议

Non-canonical inflammationPyroptosisCaspase-4/5/11TLR4Sepsis

咔咯光动力靶向降解SIRT1调节蛋白质乙酰化修饰抑制肝癌细胞生长的分子机制探究

由于类卟啉化合物咔咯中心具有更小的空腔,可与高价态金属形成更为稳定的配合物,在PDT 治疗领域有着更广泛的应用前景[1]。前期研究中,我们设计、制备了不同构型的金属咔咯配合物,发现5,10,15-三(乙氧基羰基)磷(V)咔咯(1-P)是一类潜在的高效低毒、肿瘤组织靶向性PDT 抗癌光敏剂,配合物主要聚集在肝脏部位[2]。

会议

咔咯光动力SIRT1蛋白乙酰化修饰肝癌参考

Proton production and transfer mechanism in [NiFe] hydrogenase

其他学术论文