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本文对61例胃粘膜球样异型增生的石蜡连续切片进行了观察,详细地描述了球样异型增生的组织病理学特点。把不同程度的球样异型增生分为三个等级。描述了典型的Ⅲ级球样异型增生细胞可突破腺管基底膜向间质浸润,形成初发癌灶;并通过Gordon Sweet氏染色示显了球样异型增生细胞向间质浸润,破坏基底膜瞬时图像。通过对61例球样异型增生和51例印戒细胞癌病人的年龄、性别分布特点的分析,发现两类病例女性病人的平均年龄均较男性提早10年。最后得出球样异型增生可能是印戒细胞癌的重要癌前病变的结论。
In this paper, serial paraffin sections of 61 cases of gastric dysplasia were observed, and the histopathological features of spherical dysplasia were described in detail. Different degrees of ball-shaped dysplasia are divided into three levels. It is described that typical grade III dysplasia can infiltrate the interstitial infiltrate of the adrenal basement membrane to form primary foci, and the infiltration of stroma-like dysplasia cells into the stroma is shown by Gordon Sweet’s staining, which destroys the basement membrane. Instantaneous image. Through the analysis of the age and sex distribution characteristics of 61 cases of ball-like dysplasia and 51 cases of signet-ring cell carcinoma, it was found that the average age of female patients in both types of cases was 10 years earlier than that of men. Finally, it is concluded that dysplasia of the ball type may be an important precancerous lesion of signet-ring cell carcinoma.