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目的:提高耐甲氧西林金黄色葡萄球菌(MRSA)血流感染患者应用万古霉素抗菌治疗效果。方法:临床药师与医生配合对1例肾功能衰竭合并MRSA血流感染患者应用万古霉素抗感染治疗实施药学监护。在分析疾病和用药特点、评估患者肾功能及治疗方案,结合肾脏替代治疗方案,通过监护万古霉素的谷浓度及不良反应和相互作用等方面为临床提供药学服务。结果:药师与医生紧密配合,肾功能衰竭患者应用万古霉素抗感染治疗安全、有效。结论:临床药师在特殊病人的个体化药物治疗过程中起到了积极作用。
Objective: To improve the antibacterial effect of vancomycin in patients with methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infection. Methods: Clinical pharmacists and doctors cooperated with one patient with renal failure and MRSA infection to administer vancomycin. In the analysis of the characteristics of the disease and the use of drugs, assessment of renal function and treatment of patients, combined with the renal replacement treatment program, by monitoring the valley concentration of vancomycin and adverse reactions and interactions for the clinical provision of pharmaceutical services. Results: pharmacists and doctors work closely with patients with renal failure vancomycin anti-infective treatment of safe and effective. CONCLUSIONS: Clinical pharmacists have played an active role in the individualized drug treatment of special patients.