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Curcumin is a component of turmeric, the yellow spice derived from the rhizome of Curcuma longa.It has been demonstrated to modulate multiple cell signaling pathways, including apoptosis, proliferation, angiogenesis and inflammation.In this study, we studied the signaling pathways involved in melanoma cell death after treatment with curcumin using western blotting.Colorimetric assays (MTT) assessed cell viability.